Tripartite motif containing 28
WebNov 28, 2013 · In previous mass spectrometry and coimmune precipitation studies, we identified tripartite motif-containing 28 (TRIM28; also known as transcriptional intermediary factor1β and Krüppel-associated box-associated protein-1) as a cofactor that specifically copurified with an NR2C1/NR2C2 (TR2/TR4) orphan nuclear receptor heterodimer that … WebMar 21, 2024 · TRIM28 tripartite motif containing 28 Gene ID: 10155, updated on 5-Feb-2024 Gene type: protein coding Also known as: KAP1; TF1B; RNF96; TIF1B; PPP1R157; …
Tripartite motif containing 28
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WebMar 8, 2024 · The tripartite motif-containing 28 (TRIM28/TIF1b/KAP1) protein is a transcriptional coregulator proposed as a therapeutic target for CRPC [ 6 ]. TRIM28 is significantly upregulated in metastatic... Tripartite motif-containing 28 (TRIM28), also known as transcriptional intermediary factor 1β (TIF1β) and KAP1 (KRAB-associated protein-1), is a protein that in humans is encoded by the TRIM28 gene.
WebMar 21, 2024 · The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. WebAug 25, 2024 · Protein quality control (PQC) is pivotal for eukaryotic cells to eliminate misfolded proteins and maintain cellular homeostasis. A decreased or increased capacity of PQC is associated with various diseases, e.g., neurodegenerative diseases and cancers. Recently, increasing evidences have suggested that tripartite motif-containing family …
WebAug 1, 2008 · The TRIM gene family encodes proteins involved in a broad range of biological processes and characterized by the presence of the tri partite m otif (hence the name TRIM), which consists of a R ING domain, one or two B -box motifs and a C oiled- … WebJan 23, 2024 · Tripartite motif-containing 28 (TRIM28) is an E3 ubiquitin ligase belonging to tripartite motif (TRIM) family. TRIM28 not only binds and degrades its downstream target, …
WebApr 12, 2024 · Tripartite motif containing 28 (TRIM28), also called TIF1β or KAP1, is a member of the TIF1 family proteins with a PHD domain and a bromo domain in the C …
WebOct 3, 2024 · Tripartite motif-containing 28 (TRIM28) is an impressive regulator of the epigenetic control of the antiviral immune response. This study evaluated if the … heti vapaat vuokra asunnot helsinkiWebNational Center for Biotechnology Information heti vapaat vuokra asunnotWebThe tripartite motif family ( TRIM) is a protein family. [1] Function [ edit] Many TRIM proteins are induced by interferons, which are important component of resistance to pathogens and several TRIM proteins are known to be required for the restriction of infection by lentiviruses. heti vapaat vuokra-asunnotWebMay 1, 2024 · TRIM28 (Tripartite motif-containing protein 28), a member of TRIM family, is aberrantly expressed and reportedly has different functions in many types of human cancer. However, the... heti vapaa senioriasunto turkuWebAug 1, 2024 · A decreased or increased capacity of PQC is associated with various diseases, e.g., neurodegenerative diseases and cancers. Recently, increasing evidences have suggested that tripartite... heti vapaat vuokra asunnot hyvinkääWebHuman E3 Ubiquitin Ligases. These ligases can be sorted alphabetically by Gene Symbol, Protein Name, or Class by clicking on the respective header. This information was culled primarily from several existing resources (click to open): Cell Signaling , Inc., hUbiqutome database , Qiagen Ubiquitin Ligases PCR Array , UbiProt Database , DUDE v. 1. ... heti vapaat asunnot kuopioWebJul 14, 2016 · The tripartite motif-containing 28 (TRIM28) protein, also known as KRAB domain-associated protein 1 (KAP1) or transcriptional intermediary factor 1 beta (TIF1β), … heti vippi