Nettet26. aug. 2024 · Further study identified that Atg5 and Atg7 were the targets of YTHDF2 (YTH N6-methyladenosine RNA binding protein 2). Upon FTO silencing, Atg5 and Atg7 transcripts with higher m 6 A levels were captured by YTHDF2, which resulted in mRNA degradation and reduction of protein expression, thus alleviating autophagy and … Informed consent was given by the patients or relatives to obtain human intervertebral tissue at surgery. The experimental methods were carried out in accordance with approved guidelines and the study was authorized by the ethics committee of the Second Military Medical University. The NP … Se mer Immunohistochemistry to assess Nrf2 expression was performed on cryosections of degenerated IVD tissue. The cryosections were … Se mer The experimental animals: Nrf2−/− C57BL/6J mice and wild-type C57BL/6J mice, were purchased from the Nanjing Biomedical Research Institute of Nanjing University (Nanjing, … Se mer RNA was extracted from human NP samples using Trizol (Invitrogen, Carlsbad, CA, USA) according to the manufacturer’s instructions and total RNA was measured spectrophotometrically … Se mer To assess age-related IVD degeneration in vivo, ten mice from each age group (3 months, 6 months, 9 months, and 1 year old) were used. One disc from each mouse was used for analysis. Mice were then euthanized and … Se mer
MISSION® esiRNA targeting mouse Atg7 Sigma-Aldrich
Nettet10 µM, 50-100 transfections. siRNA products generally consist of pools of three to five target-specific 19-25 nt siRNAs designed to knockdown gene expression. for independent verification of ATG7 gene silencing results, individual siRNA duplex components are also available upon request. suitable control antibody: ATG7 Antibody (B-9): sc-376212. Nettet18. okt. 2016 · microRNA-20a Inhibits Autophagic Process by Targeting ATG7 and ATG16L1 and Favors Mycobacterial Survival in Macrophage Cells microRNA-20a Inhibits Autophagic Process by Targeting ATG7 and ATG16L1 and Favors Mycobacterial Survival in Macrophage Cells . 2016 Oct 18;6:134. doi: 10.3389/fcimb.2016.00134. … goods accounting
Atg7 Mouse Sirnas Bioz Ratings For Life-Science Research
Nettet33 ATG7 Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. Sign in. Don't have an account ... Atg7. Species Mouse … Nettet1. sep. 2015 · Female rats had a tighter response to Atg7 siRNA treatment in terms of Purkinje cell survival (91.0 vs. 76.2% in Atg7 vs. control siRNA groups, respectively) … Nettet29. mai 2024 · The aim of this study was to investigate if SIRT1 directly binds and deacetylates autophagy proteins in chondrocytes and if SIRT1 positively influences … chest pain clinic medway