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Dedicator of cytokinesis 2

WebFeb 1, 2024 · Dedicator of cytokinesis 2 (DOCK2) deficiency protects mice from chronic high-fat and high-fructose (HFHF) diet–induced lung inflammation/injury. A: Body weight of DOCK2 knockout (DOCK2 −/− ) mice fed a normal chow diet or an HFHF diet for 20 weeks. WebMar 18, 2015 · Dedicator of cytokinesis 2 (DOCK2) is a novel protein factor regulating SMC phenotypic modulation and vascular remodeling. Deletion of DOCK2 blocks injury …

American Journal of Respiratory Cell and Molecular Biology

WebApr 12, 2024 · DOCK2 (dedicator of cytokinesis 2) expression was induced in human pleural fibrosis. ( A ) Hematoxylin and eosin staining in human normal and pleuritis lung suggested increased fibrosis in the visceral pleura of a patient with nonspecific pleuritis versus that in a normal control patient. WebMar 18, 2015 · Dedicator of cytokinesis 2 (DOCK2 [DK2]) deficiency attenuated injury-induced neointima formation and smooth muscle cell … lego ghostbusters light kit https://patricksim.net

Dedicator of cytokinesis protein 2 couples with lymphoid …

WebApr 11, 2024 · In this study, we explored the regulation between circular forms of dedicator of cytokinesis 1 (circDOCK1) (hsa_circ_0007142) and miR-128-3p, and its implication on the pathogenesis of breast cancer modulated by never in mitosis (NIMA) related kinase 2 (NEK2). We revealed an increase in circDOCK1 and NEK2 expression, and a decrease … WebDedicator of cytokinesis 2 (DOCK2) is a Rac activator predominantly expressed in hematopoietic cells. Although DOCK2 regulates migration and activation of leukocytes, its role in MCs remains unknown. Objective: We aimed to elucidate whether—and if so, how—DOCK2 is involved in MRGPRX2/B2-mediated MC degranulation and anaphylaxis. WebDock11 (Dedicator of cytokinesis), also known as Zizimin2, is a large (~240 kDa) protein involved in intracellular signalling networks. [5] [6] It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors (GEFs) which function as activators of small G proteins. Dock11 activates the small G protein Cdc42 . lego ghostbusters all bosses

DOCK2; Dedicator of Cytokinesis 2 SpringerLink

Category:Dedicator of Cytokinesis 2 in Cell Signaling Regulation …

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Dedicator of cytokinesis 2

circRNA新文速递丨20240412 - 知乎 - 知乎专栏

WebView/Edit Human. View/Edit Mouse. Dedicator of cytokinesis protein 10 (Dock10), also known as Zizimin3, is a large (~240 kDa) protein involved in intracellular signalling networks that in humans is encoded by the DOCK10 gene. [5] It is a member of the DOCK-D subfamily of the DOCK family of guanine nucleotide exchange factors, which function as ... WebAug 1, 2016 · Dedicator of Cytokinesis 2 (DOCK2) Deficiency Attenuates Lung Injury Associated with Chronic High-Fat and High-Fructose Diet–Induced Obesity Article Nov 2024 Am J Pathol Guoqing Qian Oluwaseun...

Dedicator of cytokinesis 2

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WebView/Edit Human. View/Edit Mouse. Dedicator of cytokinesis protein 10 (Dock10), also known as Zizimin3, is a large (~240 kDa) protein involved in intracellular signalling … WebGene ID: 104497852, updated on 12-Mar-2024. Summary Other designations. LOW QUALITY PROTEIN: dedicator of cytokinesis protein 2-like, Dedicator of cytokinesis …

WebMay 21, 2024 · Dedicator of Cytokinesis 2 (DOCK2) Silencing Protects Against Cerebral Ischemia/Reperfusion by Modulating Microglia Polarization via the Activation of the STAT6 Signaling Pathway Neuroscience. 2024 May 21;491:110-121. doi: 10.1016/j.neuroscience.2024.03.040. Epub 2024 Apr 5. Authors WebNov 17, 2024 · Dedicator of cytokinesis protein 2 (DOCK2) is a member of the cytoskeletal dynamics protein family, and is ubiquitously expressed in hematopoietic …

WebJul 12, 2024 · Dedicator of cytokinesis 2 (DOCK2) is an innate immune signaling molecule involved in vascular remodeling. However, it is unknown if DOCK2 plays a role in airway remodeling during asthma development. In this study, we found that DOCK2 is highly induced in both normal human bronchial epithelial cells (NHBECs) treated with house … WebJan 1, 2024 · DOCK2; Dedicator of Cytokinesis 2, Fig. 2 The signal transduction through DOCK2. DOCK2 transmits the signals from the several types of the integrins and …

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WebDedicator of cytokinesis 2 (DOCK2) is a CDM family protein containing DOCK homology region (DHR)-1 and DHR-2, Src-homology 3 (SH3) domain, and C-terminal polybasic … lego ghostbusters nzWebOct 14, 2008 · 1.20.1270.350 Dedicator of cytokinesis N-terminal subdomain 1 hit; 2.30.30.40 SH3 Domains 1 hit; InterPro. View protein in InterPro; IPR016024 ARM-type_fold; IPR027007 C2_DOCK-type_domain; IPR035892 C2_domain_sf; IPR026791 DOCK; More InterPro links; PANTHER. PTHR45653 DEDICATOR OF CYTOKINESIS 1 hit; lego ghostbusters pc gamesWebNov 17, 2024 · Dedicator of cytokinesis protein 2 (DOCK2) is a member of the cytoskeletal dynamics protein family, and is ubiquitously expressed in hematopoietic cells. 5 It functions as a critical ras-related C3 botulinum toxin substrate (Rac) regulator that can affect cellular activities, including migration, activation, and proliferation of lymphocytes. … lego ghostbusters gogglesWebJul 8, 2024 · Dedicator of cytokinesis 2 (DOCK2) is known to regulate diverse immune functions by activating Rac and has been recently implicated in pleural fibrosis. We now report a novel role of DOCK2 in pulmonary fibrosis development by mediating FMT. In primary normal and IPF human lung fibroblasts (HLFs), TGF-β induced DOCK2 … lego ghostbusters story packWeb2 National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, United States. Both Wiskott-Aldrich syndrome (WAS) and dedicator of cytokinesis 8 (DOCK8) deficiency are primary immunodeficiency diseases caused by mutations in genes that result in defective organization of the cytoskeleton in hematopoietic tissues. lego ghostbusterstm ecto-1WebFeb 1, 2024 · Dedicator of cytokinesis 2 (DOCK2) is induced by tumor necrosis factor-α (TNF-α) at the transcriptional level in human lung fibroblasts (HLFs). A: Primary HLFs#1 … lego ghostbusters towerWebApr 12, 2024 · 2.细胞质分裂作用因子1的环状形式通过海绵化miR-128-3p来抑制有丝分裂相关激酶2的表达,从而促进乳腺癌的进展. 标题:Circular forms of dedicator of cytokinesis 1 promotes breast cancer progression by derepressing never in mitosis related kinase 2 via sponging miR-128-3p. IF:4.109. 期刊:Environ Toxicol lego giant man instructions