Cinnamic acid inhibition cancer cells
WebNov 30, 2024 · The anti-cancer activity of cinnamic acid derivatives was measured according to Madhunapantula et al., 2008 . 0.5 x 10 4 colon (HCT-116 and HCT-15) and … WebNov 1, 2024 · Thus, inhibition of CBR1 can increase the therapeutic effect of DOX. In the present study, we used a group of new synthetized cinnamic acid (CA) derivatives to …
Cinnamic acid inhibition cancer cells
Did you know?
WebCinnamic acid belongs to phenolic-acid class of polyphenols, one of the most abundant plant secondary metabolites. These substances are widely studied because of plethora … WebOct 21, 2024 · Incubation of human colorectal cancer cells in the presence of cinnamic acid at concentration higher than 10 mM resulted in reduced cell viability (IC50 13.6 mM). ... The mechanism is attributed to the lower expression of some drug resistance proteins, inhibition of cell proliferation, and promotion of apoptosis (Lu et al. 2024).
WebBackground & objective: Recently, the research showed that cinnamic acid (CINN) could inhibit some cancer cells. This study was designed to investigate the effects of alpha … WebCinnamic acid containing an aryl ring with α, β-unsaturated ketone, was reported to have anticancer activity. Therefore, both chalcone and cinnamic acid have been adapted as versatile structural moieties in many cases of cancer drug development [ 30 ].
WebFeb 26, 2024 · Propolis extract or components was reported to be cytotoxic to several cancer cells [20, 21] and to induce autophagy in breast cancer cells [9].In order to elucidate whether and what kind of propolis components exhibits the above actions on prostate cancer CWR22Rv1 cells, the cytotoxic effects of eight cinnamic acid … WebNov 30, 2024 · However, treating the colon cancer cells with DHCA for 48h showed much better HDAC inhibitory effect (80% and 77% HDAC inhibition, respectively in HCT116 …
WebJul 1, 2024 · In the current study, we show the inhibitory effects of cinnamic acid derivatives, including caffeic acid phenethyl ester (CAPE, 1), on the growth of breast and prostate cancer cells. Among the compounds examined, 3,4,5-trihydroxycinnamic acid …
WebMar 25, 2015 · Although one of the best characterized inhibitors, α-cyano-4-hydroxycinnamic acid (α-CCA), possesses a 10-fold selectivity for MCT1 compared to other subtypes (Figure 1) [22], it also shows ... braun thermoscan lens filter lf40WebTo design & optimize trans-cinnamic acid loaded PLGA nanoparticles & assess its inhibitory effect on epithelial-mesenchymal transition triple-negative BC. ... the Impact of Optimized Trans-Cinnamic Acid-Loaded PLGA Nanoparticles on Epithelial to Mesenchymal Transition in Breast Cancer . Fulltext; Metrics; Get Permission; Cite this article; braun thermoscan nzWebNov 30, 2024 · A search for naturally occurring HDAC inhibitors continues due to the adverse effects associated with known HDAC inhibitors like SAHA and TSA. Therefore … braun thermoscan operating instructionsWebApr 12, 2024 · At 1.5 µM cinnamic acid addition, the biomass level and chrysin production demonstrated a sharp decrease of 1.62 g/L and 3.80 mg/L, respectively. Cinnamic acid is a key metabolite that regulates several metabolic pathways in microbes. In plants, it acts as an allelochemical that influences seed germination and root growth. braun thermoscan lf 20 lens filtersWebP-Coumaric acid, an abundant isomer of cin- namic acid, inhibits the colon cancer cell lines by in- creasing the ROS levels, decreasing the mitochondrial membrane potential and inhibiting the cell cycle at sub G1 phase [52]. Esters of cinnamic acids are more potent when compared to the hydroxylated or the methoxylated versions [40]. braun thermoscan newbornWebJul 18, 2024 · The antioxidant and biological activities of Physalis peruviana have been reported in extracts of the calyxes, leaves, stems, and merely in fruits. These extracts have been shown to inhibit the growth of different cancer cell lines and exhibit protective effects in liver and other cells, as well as exhibit anti-inflammatory activity. 11,12 Some studies … braun thermoscan pc200 probe coversWebCA treatment increased the levels of lipid peroxidation in Hela and ME-180 cells. Among all the concentrations (30, 40, and 50 μg/ml) tested, 50 μg of CA showed maximum levels of thio-barbituric acid reactive substances (TBARS), CD, and LHP in HeLa and ME-180 cells (Figure 73.5).Pro-oxidant activity of hydroxycinnamic acids on DNA damage and lipid … braun thermoscan plus hm4